{"id":3765,"date":"2021-02-26T04:30:48","date_gmt":"2021-02-26T09:30:48","guid":{"rendered":"https:\/\/usmlerx.wpengine.com\/?post_type=podcast&#038;p=3765"},"modified":"2021-02-25T22:09:26","modified_gmt":"2021-02-26T03:09:26","slug":"peptic-ulcer-disease","status":"publish","type":"podcast","link":"https:\/\/usmle-rx.com\/podcast\/peptic-ulcer-disease\/","title":{"rendered":"Peptic Ulcer Disease"},"content":{"rendered":"<div class=\"relative ng-tns-c548-39 ng-star-inserted\">\n<p id=\"CP_DIG0037-VG02be5d48f0359f4fd7b9284eef0bf7fadc\" class=\"section-container editable-content medium-editor-element\" role=\"textbox\" data-rxannotationdata=\"content.text\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">Ulcers are open sores that develop in the skin or mucous membranes. In peptic ulcer disease (PUD), painful sores develop, most commonly in the lining of the stomach, duodenum, or both. PUD arises when there is an imbalance between protective factors (eg, mucosal barrier) and damaging factors (eg, hydrochloric acid).<\/p>\n<\/div>\n<div class=\"relative ng-tns-c548-39 ng-star-inserted\">\n<p id=\"CP_DIG0037-VG03af86d239dc424642b276ee7927b9c28c\" class=\"section-container editable-content medium-editor-element\" role=\"textbox\" data-rxannotationdata=\"content.text\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">How does PUD differ from gastritis? Gastritis describes inflammation of the stomach lining, which can be acute or chronic. With gastritis, the submucosae are not harmed, and the muscular stomach wall remains intact. In PUD, there is ulceration through the mucosa into underlying tissue, which can reach into the submucosa and muscular layer. It may cause perforation and bleeding. Chronic gastritis can be a predisposing factor, but it is not required to diagnose PUD.<\/p>\n<p role=\"textbox\" data-rxannotationdata=\"content.text\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">After listening to this AudioBrick, you should be able to:<\/p>\n<ul class=\"section-container badge-list learning-objective-badge-list ng-tns-c548-39\">\n<li class=\"mat-badge mat-badge-warn ng-tns-c548-39 mat-badge-overlap mat-badge-above mat-badge-before mat-badge-medium ng-star-inserted\" data-rxvignette=\"true\" data-rxannotationidentifier=\"CP_DIG0037.2-LO00\"><span class=\"editable-content ng-tns-c548-39 medium-editor-element\" role=\"textbox\" data-rxannotationdata=\"learningObjective\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">Define peptic ulcer disease (PUD) and state the most important risk factors.<\/span><\/li>\n<li class=\"mat-badge mat-badge-warn ng-tns-c548-39 mat-badge-overlap mat-badge-above mat-badge-before mat-badge-medium ng-star-inserted\" data-rxvignette=\"true\" data-rxannotationidentifier=\"CP_DIG0037.2-LO01\"><span class=\"editable-content ng-tns-c548-39 medium-editor-element\" role=\"textbox\" data-rxannotationdata=\"learningObjective\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">Describe the morphologic and pathogenetic features of\u00a0<em>Helicobacter<\/em>\u00a0<em>pylori<\/em><em>\u00a0<\/em>and the histology of gastric lesions with which it is associated.<\/span><\/li>\n<li class=\"mat-badge mat-badge-warn ng-tns-c548-39 mat-badge-overlap mat-badge-above mat-badge-before mat-badge-medium ng-star-inserted\" data-rxvignette=\"true\" data-rxannotationidentifier=\"CP_DIG0037.2-LO02\"><span class=\"editable-content ng-tns-c548-39 medium-editor-element\" role=\"textbox\" data-rxannotationdata=\"learningObjective\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">Explain gastrinoma and Zollinger-Ellison syndrome as a cause of PUD.<\/span><\/li>\n<li class=\"mat-badge mat-badge-warn ng-tns-c548-39 mat-badge-overlap mat-badge-above mat-badge-before mat-badge-medium ng-star-inserted\" data-rxvignette=\"true\" data-rxannotationidentifier=\"CP_DIG0037.2-LO03\"><span class=\"editable-content ng-tns-c548-39 medium-editor-element\" role=\"textbox\" data-rxannotationdata=\"learningObjective\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">Describe the typical clinical presentation of PUD and the tests used to make a diagnosis.<\/span><\/li>\n<li class=\"mat-badge mat-badge-warn ng-tns-c548-39 mat-badge-overlap mat-badge-above mat-badge-before mat-badge-medium ng-star-inserted\" data-rxvignette=\"true\" data-rxannotationidentifier=\"CP_DIG0037.2-LO04\"><span class=\"editable-content ng-tns-c548-39 medium-editor-element\" role=\"textbox\" data-rxannotationdata=\"learningObjective\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">Explain the most common treatment strategies for PUD.<\/span><\/li>\n<li class=\"mat-badge mat-badge-warn ng-tns-c548-39 mat-badge-overlap mat-badge-above mat-badge-before mat-badge-medium ng-star-inserted\" data-rxvignette=\"true\" data-rxannotationidentifier=\"CP_DIG0037.2-LO05\"><span class=\"editable-content ng-tns-c548-39 medium-editor-element\" role=\"textbox\" data-rxannotationdata=\"learningObjective\" data-medium-editor-element=\"true\" aria-multiline=\"true\" data-medium-editor-editor-index=\"1\" data-placeholder=\"Type your text\">List the potential adverse outcomes of untreated PUD.<\/span><\/li>\n<\/ul>\n<p>You can also check out the original brick on Peptic Ulcer Disease from our Gastrointestinal collection, which is <a href=\"https:\/\/usmle-rx.scholarrx.com\/rx-bricks\/brick\/CP_DIG0037\">available for free<\/a>.<\/p>\n<p>Learn more about\u00a0<a href=\"https:\/\/usmlerx.wpengine.com\/products\/rx-bricks\/\">Rx Bricks<\/a>\u00a0by signing up for a free USMLE-Rx account:\u00a0<a href=\"https:\/\/usmlerx.wpengine.com\/free-bricks\/\">www.usmle-rx.com<\/a><\/p>\n<p>You will get 5 days of full access to our\u00a0<a href=\"https:\/\/usmlerx.wpengine.com\/products\/step-1-rx360\/\">Rx360+<\/a>\u00a0program, including nearly 800 Rx Bricks.\u00a0 After the 5-day period, you will still be able to access over\u00a0<strong>150 free bricks<\/strong>, including the entire collections for\u00a0<strong>General Microbiology<\/strong>\u00a0and\u00a0<strong>Cellular and Molecular Biology<\/strong>.<\/p>\n<p>***<\/p>\n<p>If you enjoyed this episode, we\u2019d love for you to leave a review on\u00a0<a href=\"https:\/\/podcasts.apple.com\/us\/podcast\/the-rx-bricks-podcast\/id1530646481\">Apple Podcasts<\/a>.\u00a0 It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world.<\/p>\n<p>Follow\u00a0<a href=\"https:\/\/usmlerx.wpengine.com\/\">USMLE-Rx<\/a>\u00a0at:<br \/>\nFacebook:\u00a0<a href=\"http:\/\/www.facebook.com\/usmlerx\">www.facebook.com\/usmlerx<\/a><br \/>\nBlog:\u00a0<a href=\"http:\/\/www.firstaidteam.com\/\">www.firstaidteam.com<\/a><br \/>\nTwitter:\u00a0<a href=\"https:\/\/twitter.com\/firstaidteam\">https:\/\/twitter.com\/firstaidteam<\/a><br \/>\nInstagram:\u00a0<a href=\"https:\/\/www.instagram.com\/firstaidteam\/\">https:\/\/www.instagram.com\/firstaidteam\/<\/a><br \/>\nYouTube:\u00a0<a href=\"http:\/\/www.youtube.com\/USMLERX\">www.youtube.com\/USMLERX<\/a><\/p>\n<p>Learn how you can access over 150 of our bricks for FREE:\u00a0<a href=\"https:\/\/usmlerx.wpengine.com\/free-bricks\/\">https:\/\/usmlerx.wpengine.com\/free-bricks\/<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"Ulcers are open sores that develop in the skin or mucous membranes. In peptic ulcer disease (PUD), painful sores develop, most commonly in the lining of the stomach, duodenum, or both. PUD arises when there is an imbalance between protective factors (eg, mucosal barrier) and damaging factors (eg, hydrochloric acid). How does PUD differ from&hellip;","protected":false},"author":21,"featured_media":3766,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"sync_status":"synced","episode_type":"audio","audio_file":"https:\/\/episodes.castos.com\/5f410b62d04ef1-00454701\/Peptic-Ulcer-Disease-AB-2021.mp3","podmotor_file_id":"400034","podmotor_episode_id":"370047","castos_file_data":"","cover_image":"","cover_image_id":"","duration":"00:24:48","filesize":"18.7 mb","filesize_raw":"19560988","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"full"},"tags":[52,53,54,55,65],"series":[133],"class_list":["post-3765","podcast","type-podcast","status-publish","has-post-thumbnail","hentry","tag-usmle","tag-first-aid","tag-rx-bricks","tag-gastrointestinal-bleeding","tag-usmle-rx","series-the-rx-bricks-podcast"],"acf":[],"episode_featured_image":"https:\/\/usmle-rx.com\/wp-content\/uploads\/2021\/02\/image-3.png","episode_player_image":"https:\/\/usmle-rx.com\/wp-content\/uploads\/2020\/09\/AudioBricks_CoverArt-1.png","download_link":"https:\/\/chtbl.com\/track\/EB2DCC\/usmle-rx.com\/podcast-download\/3765\/peptic-ulcer-disease.mp3","player_link":"https:\/\/chtbl.com\/track\/EB2DCC\/usmle-rx.com\/podcast-player\/3765\/peptic-ulcer-disease.mp3","audio_player":null,"episode_data":{"playerMode":"dark","subscribeUrls":{"apple_podcasts":{"key":"apple_podcasts","url":"https:\/\/podcasts.apple.com\/us\/podcast\/the-rx-bricks-podcast\/id1530646481","label":"Apple Podcasts","class":"apple_podcasts","icon":"apple-podcasts.png"},"google_play":{"key":"google_play","url":"https:\/\/www.google.com\/podcasts?feed=aHR0cHM6Ly93d3cudXNtbGUtcnguY29tL2ZlZWQvcG9kY2FzdA%3D%3D","label":"Google Play","class":"google_play","icon":"google-play.png"},"overcast":{"key":"overcast","url":"https:\/\/overcast.fm\/itunes1530646481\/the-rx-bricks-podcast","label":"Overcast","class":"overcast","icon":"overcast.png"},"spotify":{"key":"spotify","url":"https:\/\/open.spotify.com\/show\/6difsNR0giFPpNfJM2e5l2","label":"Spotify","class":"spotify","icon":"spotify.png"},"stitcher":{"key":"stitcher","url":"https:\/\/www.stitcher.com\/show\/the-rx-bricks-podcast","label":"Stitcher","class":"stitcher","icon":"stitcher.png"}},"rssFeedUrl":"https:\/\/usmle-rx.com\/feed\/podcast\/the-rx-bricks-podcast","embedCode":"<blockquote class=\"wp-embedded-content\" data-secret=\"v1gIDlCreC\"><a href=\"https:\/\/usmle-rx.com\/podcast\/peptic-ulcer-disease\/\">Peptic Ulcer Disease<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/usmle-rx.com\/podcast\/peptic-ulcer-disease\/embed\/#?secret=v1gIDlCreC\" width=\"500\" height=\"350\" title=\"&#8220;Peptic Ulcer Disease&#8221; &#8212; USMLE-Rx\" data-secret=\"v1gIDlCreC\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! 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